Specialist: Sanjay

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The consistent cleaning of dedusting systems in the pharmaceutical industry is of great importance to ensure product safety and quality. Based on the search results, the following points can be emphasised:

## Cleaning protocols

Clear cleaning protocols are essential to ensure standardised and seamless cleaning. These should contain detailed instructions for the individual steps, responsibilities, documentation requirements and test procedures [1].

## Regular maintenance and inspection

Regular maintenance and inspection of dust extraction systems is essential in order to recognise and remove contamination at an early stage. Areas that are difficult to access should also be considered [1].

## Surface finish

The choice of suitable surface materials and structures can improve the cleanability of the systems. Smooth, chemically resistant surfaces with as little roughness as possible make cleaning easier [5].

## Validation and monitoring

The effectiveness of the cleaning processes must be ensured through validation and continuous monitoring of the systems. Microbiological and particle-based analyses can be used for this purpose [1][5].

## Employee training

Thorough training of employees on cleaning procedures, safety aspects and documentation requirements is essential for consistent implementation [1].

By combining these measures, reliable and reproducible cleaning of the dedusting systems in pharmaceutical production plants can be guaranteed and thus fulfil the highest quality standards [1][5].

Citations:
[1] https://www.semanticscholar.org/paper/c68bb7b1f0f49002b93ce180eb81d2ad57f67fd2
[2] https://www.semanticscholar.org/paper/2997fbcb899d0ab852ad912e0f077137eed27f34
[3] https://www.semanticscholar.org/paper/d1654c595fc4806218331da0b0bddbd77d809947
[4] https://www.semanticscholar.org/paper/9c597a5b5d605042d297a76aefd9acf783dd2554
[5] https://www.semanticscholar.org/paper/1cde44daa2553f097895ba65188722e082a39785
[6] https://www.semanticscholar.org/paper/302ff168a98ab0d0b746a5dd27e3d8976122a86b
[7] https://www.semanticscholar.org/paper/06f0a703f670943f33d8e4678624023f3d830e68
[8] https://www.semanticscholar.org/paper/f1c440637113d4b158f79cad595e1f1c21a79d95
[9] https://www.semanticscholar.org/paper/b778061e5034d89f5a2c013aa3c3ba749f89b318
[10] https://www.semanticscholar.org/paper/2aeaa6a9447ac763ed0a5efdecb2a2d660e60665
[11] https://www.semanticscholar.org/paper/075b3d72c70eb3d4338b2f9eff53be3396aa7d52
[12] https://www.semanticscholar.org/paper/799b526514516f47e6a8ff01edb969ad6a5bb2d5
[13] https://www.semanticscholar.org/paper/cfa14794983b3cdc933c0931a3d11f2e73592185
[14] https://www.semanticscholar.org/paper/05b80e032eca43aea1a932a0f0582ceec4a868df

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